Aspirus Media Center

The Critical Role of Medication Management Before Surgery

2/6/2025

Olivia Bishop, Aspirus Pharmacy Resident

Managing medications before surgery is a vital step to ensure patient safety and a smooth recovery. Certain medications can increase the risk of complications, such as excessive bleeding, blood clots, or unexpected reactions during the procedure. Understanding which medications to stop—or adjust—is a critical part of surgical preparation. 

 

“Medications can alter how your body works and increase your risk of complications during surgery,” explains Olivia Bishop, a pharmacy resident at Aspirus Health. “That’s why it’s so important to know which medications to stop and when.” 

 

Some drugs, such as those used for diabetes and weight loss, can delay how quickly the stomach empties. This can leave food in the stomach even after fasting, increasing the risk of regurgitation or choking during surgery. Similarly, blood-thinning medications, such as anticoagulants, can heighten the risk of excessive bleeding if not properly managed. 

 

Herbal supplements and over-the-counter (OTC) medications can also increase the risk of complications if not stopped before surgery. According to the National Center for Biotechnology Information (NCBI), supplements like ginkgo biloba, garlic, and melatonin may increase bleeding risks, especially when combined with certain medications. Patients are generally advised to stop these supplements at least two weeks prior to surgery, or as directed by their provider, to reduce the risk of complications. 

 

“If you take anticoagulants, herbals or supplements, it’s important to talk to your provider,” Bishop advises. “We want to ensure you aren’t putting yourself at an increased risk of bleeding.” 

 

Patients typically receive detailed pre-operative instructions that outline which medications to stop and when. If instructions are unclear or missing, Aspirus Health experts urge patients to contact their surgeon or healthcare provider for clarification. 

 

“Some medications might be more dangerous to stop suddenly,” Bishop says. Medications like antidepressants, anti-anxiety drugs, and certain blood pressure treatments may need to be continued or gradually tapered off under a doctor’s supervision. “It’s always better to ask your surgeon or health care provider and get clear guidance.” 

 

Proactively discussing your medications with your health care team is one of the best ways to ensure a safe and smooth surgical experience. 

 

 

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